optiflex genesis instruction 4

FLAVIN

Isotonic Riboflavin Ophthalmic Solution

Sterile and Preservative-free Solution

Flavin is a sterile, preservative-free ophthalmic solution containing Riboflavin 0.1% and Dextran in saline buffer for external ocular usage. They are used as a photo sensitizing agent in Corneal Collagen cross linking as a treatment for patients with Keratoconus and Corneal Ectasia in different corneal conditions.

Advantages of Cross Linking Treatment with Flavin

Safe & effective in the management of progressive keratoconus

Cumulative visual acuity of 20/40 or better in 30% of eyes

92% eyes had no change in CDVA at 12 months postoperatively

4% eyes gains 1 line of CDVA at 12 months postoperatively

62% eyes achieve refractive SE range of +/- 1D

26% eyes achieve refractive astigmatism with in +/- 1D

No or minimal corneal haze after 12 months

No significant difference in ECD in Post op as compared to Pre – op

No immediate or long term post op vision threatening complications

Technical Specifications

FlavinIsotonic Riboflavin Ophthalmic Solution (0.1%)
COMPOSITIONEach ml contains

Riboflavin Sodium Phosphate BP

(Equivalent to base Riboflavin)…………………….0.1% w/v

Dextran P500…………………………………………….20.0% w/v

Phoshpate Buffar Saline……………………………..q. s.

SUPPLY

Flavin is supplied in ready to single use sterile Prefilled Syringe of 1.0 ml / 3.0 ml with sterile single use Cannula.